Fully neutralising antibodies to SARS-CoV-2

May 5, 2020

CORAT generated fully neutralising coronavirus antibodies protecting against SARS-CoV-2 infection, as confirmed by the Helmholtz Center for Infection Research

Infection of cells (in cell culture) with SARS-CoV2 isolates from a COVID19 patient lead to their lysis, indicated by rounding and loss of confluence (upper left panel). Uninfected cells (upper right) grow normally (no dead round dots). Lower right: Adding the CORAT antibody to infected cells completely protected the cells from infection for 5 days, while a negative control antibody (lower left panel) did not protect the cells (Fotos: light microscopy).
(Data: HZI, Prof. Čičin-Šain)

“This result represents a crucial milestone in development of an effective therapy for Covid-19.” (Dr. Thomas Schirrmann)

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